
Syed Intakhab Alam
Hamad General Hospital, QatarTitle: Chronic recurrent multifocal osteomyelitis and its management
Abstract
Chronic recurrent multifocal
osteomyelitis (CRMO) is an inflammatory disorder of bones first reported by
Giedion et al. in 1972. It is a disease of childhood, comparable to SAPHO
(synovitis, acne, pustulosis, hyperostosis, and osteitis) in adults. CRMO
presents with pain and swelling overlying the involved bones. Inflammatory
markers are usually raised and X-rays usually show sclerotic lesions. MRI
demonstrates the extent of the lesions accurately and associated soft tissue
changes. Nonsteroidal anti-inflammatory drugs (NSAIDs) and corticosteroids are
the mainstays of the management. We report three patients who presented with
bone pains. Extensive workup and radiological modalities along with clinical
findings supported the diagnosis of CRMO. This article highlights important
clinical presentations, radiological findings, and various management options.
From our cases and review of the literature, we conclude that CRMO is a
diagnosis of exclusion and biopsy should be performed to surely rule out the
underlying malignant processes. Most patients respond well to NSAIDs and
corticosteroids; however, interleukin 1 inhibitors and the role of DMARDs role
have also been illustrated in the literature.
Biography
Syed Alam is an associate consultant
in the department of clinical imaging at Hamad general hospital, Doha, Qatar.
He is In-charge of the research committee in the department of clinical imaging
and has been awarded the Best Teaching Faculty Award for the year 2014-2015. He
was also the guest speaker in the Annual Scientific Meeting European Society of
Musculoskeletal Radiology (ESSR) 2014, Riga, Latvia. He has been a speaker and
tutor in the Qatar MSK Ultrasound Course every year from 2014-2021. He is a
member of the European Society of Musculoskeletal Radiology and the Asian
Musculoskeletal Radiology Society. He has published many articles in radiology
journals and delivered many lectures in the Asian Musculoskeletal Society.