Shayan Amiri
University of Medical Sciences, IranTitle: Moderately elevated erythrocyte sedimentation rate (ESR) or C-reactive protein (CRP) in patients with no clinical signs or symptoms of infection is not a contraindication for total knee arthroplasty: a retrospective cohort study
Abstract
It is unclear whether patients with elevated preoperative levels of
erythrocyte sedimentation rate (ESR) or C-reactive protein (CRP) are more prone
to periprosthetic joint infection (PJI) after total knee arthroplasty (TKA).
The authors aimed to determine how preoperative moderate elevation of ESR or
CRP in patients without clinical signs or symptoms of infection is associated
with the risk of PJI after TKA surgery.In a prospective study, 315 patients who
were elected for unilateral TKA were included, including 237 patients with
preoperative normal ESR and CRP, 46 patients with moderate preoperative
elevation of ESR (less than 50 mm/hr), and 32 patients with moderate
preoperative elevation of CRP (less than 24 mg/dL). Patients with both ESR and
CRP elevation were not included in the study. primary TKA was done using a
standard medial parapatellar approach under general anesthesia. Overall rate of
infection was 0.3% (1 in 320 patients) at a mean follow-up period of 19 ± 5.3
mo. This infection occurred in a patient with normal preoperative ESR and CRP
(1 in 237 patients, 0.4%). No infection occurred in 78 patients in either the
ESRelevated or the CRP-elevated group. Accordingly, the rate of infection was
not significantly different between the two groups (P = 0.83) Moderate
preoperative elevations of ESR or CRP do not increase the rate of
periprosthetic joint infection in patients undergoing total knee arthroplasty.
Biography
Shayan Amiri pursuing orthopaedic
surgery residency in Iran University of Medical Sceinces. He completed his MD
in Shahid Beheshti University of Medical Sciences in 2017. He was chosen as the
best researcher of the Iran university in 2021. He can speak English and French
fluently. He has published about 10 research relevant to orthopaedic surgery in
the past 2 years and also a book about orthopaedics tumors in nova publication.
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